The manufacturer of Apexatropin claims that are no side effects because the product is all natural. However, we think that this is actually because of the micro amounts of the active ingredients used in the formula. It's not very certain, though, with the case of the proprietary blend because there is no clear indication as to how much substances were used for the blend. Allergic reactions may be expected particularly in people who are sensitive to any of the ingredients used, such as shellfish.